CJC-1295 No-DAC (also known as Mod GRF 1-29) is a short-acting growth hormone-releasing hormone (GHRH) analog used to study the stimulation of the body's own growth hormone (GH) pulsatile secretion.
Key Features
Short half-life, approximately 30 minutes.
Unlike CJC-1295 with DAC, it does not release cyclically.
More closely resembles the body's natural GH secretion rhythm.
Often used in conjunction with GHRP analogs such as Ipamorelin in research.
Reconstitution Method (5 mg vial)
Common Reconstitution Ratio
5 mg lyophilized powder
Add 3.0 mL of antibacterial water
Obtained Concentration
1.67 mg/mL
That is, 1 mL = 1667 mcg
U-100 Insulin Injector Conversion
Dose
Syringe Markings
100 mcg
6 units (0.06 mL)
200 mcg
12 units (0.12 mL)
250 mcg
15 units (0.15 mL)
300 mcg
18 units (0.18 mL)
Example of a Dose Study Protocol
Cycle
Daily Dosage
Weeks 1–4
200 mcg
Weeks 5–8
250 mcg
Weeks 9–12 (Optional)
300 mcg
Recommended Usage Cycle
Common Study Cycle: 8–12 weeks
Can be extended or adjusted depending on study objectives
Injection sites need to be rotated (abdomen, legs, etc.)
It is recommended to inject on an empty stomach (to avoid high insulin levels interfering with GH secretion).
Storage and Stability
Unreconstituted
Recommended storage: -20 °C or lower (freezing)
Long-term storage: -80 °C
After Reconstitution
Refrigerate at 2–8 °C
Avoid repeated freezing/thawing
Store away from light
Reconstitution date and concentration are recommended
Caution
Pour water slowly along the side of the bottle
Do not shake vigorously
Frequently Asked Questions (FAQ)
Q1: What is CJC-1295 No-DAC (Mod GRF 1-29)?
It is a short-acting growth hormone-releasing hormone (GHRH) analog utilized to study the stimulation of natural GH pulsatile secretion.
Q2: How does CJC-1295 No-DAC differ from CJC-1295 with DAC?
Unlike the DAC version, CJC-1295 No-DAC has a short half-life (around 30 minutes), does not release cyclically, and more closely mimics the natural rhythm of growth hormone release.
Q3: How should a 5 mg vial of CJC-1295 No-DAC be reconstituted?
Add 3.0 mL of antibacterial water into the 5 mg lyophilized powder vial. This yields a solution with a concentration of 1.67 mg/mL (1667 mcg/mL).
Q4: Why is it recommended to administer on an empty stomach?
Administering on an empty stomach prevents elevated insulin levels from interfering with the natural secretion of growth hormone during research.
Q5: What are the proper storage requirements after reconstitution?
Once reconstituted, the solution should be kept refrigerated at 2–8 °C, stored away from light, and protected from repeated freeze/thaw cycles.
