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High-Quality Ethylamino Ethanol Factory & Companies

Global Chemical Whitepaper & Procurement Guide: 2-(Ethylamino)ethanol Technical Insights, Industrial Scale Production, Synthesis Kinetics, Regulatory Frameworks, and Supply Chain Solutions.

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Executive Overview & Technical Profile of Ethylamino Ethanol

Comprehensive evaluation of 2-(Ethylamino)ethanol (CAS 110-73-6): Structural chemistry, purity grades, physical dynamics, and industrial application parameters.

Understanding 2-(Ethylamino)ethanol (CAS 110-73-6)

Ethylamino Ethanol (also recognized under IUPAC nomenclature as 2-(Ethylamino)ethanol, N-Ethylethanolamine, or EAE) represents a pivotal bifunctional organic compound integrating both primary hydroxy and secondary amino functional groups. Featuring the molecular formula C4H11NO and a molar mass of 89.14 g/mol, this versatile amino alcohol plays a critical structural and catalytic role across high-end chemical synthesis, API manufacturing, specialty coatings, and gas treatment architectures.

As a leading global chemical supply partner, our factory operations emphasize high-yield, high-purity (≥99.5% by GC) manufacturing of Ethylamino Ethanol. Utilizing advanced micro-channel reactor technologies and automated distillation cascades, we guarantee absolute batch-to-batch consistency, eliminating critical contaminants such as unreacted ethylamine, ethylene oxide traces, and water impurities.

Technical Assurance: Our standard industrial grade meets stringent international pharmaceutical intermediate standards, supported by full Certificate of Analysis (CoA), REACH registration documentation, and comprehensive MSDS/SDS safety data sheets.

Standard Technical Specifications

Parameter Specification Range Testing Method
Chemical Name 2-(Ethylamino)ethanol / N-Ethylethanolamine IUPAC Standard
CAS Registry No. 110-73-6 CAS Database
Purity (GC) ≥ 99.5% Gas Chromatography
Water Content ≤ 0.20% Karl Fischer Titration
Density (20°C) 0.914 - 0.918 g/cm³ Pycnometer / ASTM D4052
Refractive Index (n20/D) 1.438 - 1.442 Refractometry
Appearance Clear, Colorless to Light Yellow Liquid Visual Inspection

Global Infrastructure & Production Impact

Quantifying our manufacturing footprint, compliance standard, and international distribution metrics.

250,000 m²
Factory Footprint
99.5%+
Standard Purity Rate
10+
Global Export Hubs
ISO/cGMP
Quality Systems

Macro Industrial Solutions & Global Application Matrix

How high-grade Ethylamino Ethanol empowers diverse sectors ranging from life science synthesis to environmental acid gas scrubbing.

Active Pharmaceutical Synthesis

Ethylamino Ethanol serves as a vital precursor in the total synthesis of active pharmaceutical ingredients (APIs), including antihistamines, local anesthetics, and cardiovascular compounds. Its dual functional group allows precise regioselective functionalization in complex molecular frameworks.

Gas Sweetening & Acid Gas Scrubbing

In natural gas refining and petrochemical processing, N-Ethylethanolamine acts as a selective absorbent amine for hydrogen sulfide (H₂S) and carbon dioxide (CO₂). It provides superior thermal stability and lower energy requirements during solvent regeneration stages.

Corrosion Inhibitors & Surface Fluids

Formulated into metalworking fluids, industrial lubricants, and boiler water treatment systems, EAE acts as an effective vapor-phase corrosion inhibitor and pH stabilizer, shielding ferrous and non-ferrous metals against acid oxidation.

Specialty Polymers & Coatings

Utilized as a chain extender and neutralizer in waterborne polyurethane dispersions (PUDs), acrylic resins, and cationic electrodeposition coatings, improving mechanical flexibility, adhesion, and chemical resistance parameters.

Agrochemical Intermediates

EAE functions as a fundamental building block in synthesizing crop protection agents, selective herbicides, and fungicide derivatives, facilitating systemic biological activity and enhanced rainfastness in field formulations.

Electronic Chemicals & Etching Cleaners

High-purity electronic grade Ethylamino Ethanol is applied in semiconductor photoresist stripping formulations and post-etch residue removers due to its rapid chelating effect and minimal trace metal ionic content.

Technical Synthesis Routes & Quality Control Framework

Inside our chemical reaction kinetics, purification infrastructure, and rigorous analytical quality control.

Synthesis Route Engineering

The industrial manufacturing of Ethylamino Ethanol is primarily driven by the liquid-phase nucleophilic ring-opening reaction of ethylene oxide (EO) with excess monoethylamine (MEA) under controlled pressure and temperature regimes:

C₂H₅NH₂ + C₂H₄O → C₂H₅NH-CH₂CH₂OH + Heat

To prevent secondary over-ethoxylation (which generates unwanted N-ethyldietanolamine side-products), our facility leverages continuous micro-channel reactors operating under a high ethylamine-to-ethylene oxide molar ratio. Subsequent multi-stage vacuum fractioning removes excess ethylamine for recycle loops, yielding top-tier purity EAE.

Analytical Quality Validation Protocol

Every production batch undergoes exhaustive multi-method analytical verification before release from our cGMP laboratory setup:

  • Gas Chromatography (GC-FID): Ensures organic purity exceeds 99.5% while monitoring trace di-alkanolamine residues.
  • Karl Fischer Coulometric Titrator: Maintains moisture levels strictly below 0.20% to prevent degradation in water-sensitive organic reactions.
  • ICP-MS Spectrometry: Guarantees heavy metal impurity controls (Pb, As, Cd, Hg < 1 ppm) for pharmaceutical-grade requests.
  • Colorimetry (APHA): Monitors clarity levels to maintain color indices below APHA 15.

Global Supply Chain & Commercial Landscape

Market dynamics, supply chain security, and regional procurement optimization for chemical buyers.

North American Market Demand

High demand driven by the oil & gas treatment sector for acid gas removal and specialized pharmaceutical synthesis hubs. Strict EPA and TSCA compliance is mandatory for all imported tonnage.

European Union & REACH Mandates

European chemical sectors prioritize low-VOC, REACH-registered chemical intermediates. Our fully compliant supply chain offers frictionless import capabilities across Germany, France, and Benelux markets.

Asia-Pacific Industrial Expansion

Rapid expansion in agrochemical synthesis and water-based coating manufacturing across East and Southeast Asia makes Asia-Pacific the fastest-growing consumption hub for Ethylamino Ethanol derivatives.

Technology Roadmap & Sustainable Innovation (2025–2035)

Driving green synthesis engineering, lower carbon footprint manufacturing, and continuous catalytic improvements.

Green Amination Technologies

We are actively developing direct catalytic bio-ethanol amination processes to replace petrochemical ethylene oxide feedstocks. This green route aims to reduce net carbon intensity by over 40% while preserving high product selectivities.

Process Intensification & AI Monitoring

Integrating machine learning optimization algorithms inside our continuous flow synthesis loops allows real-time thermal balancing and impurity detection, bringing process yield efficiencies to unprecedented levels above 99.8%.

About Gentolex Group

Gentolex’s goal is to create opportunities connecting the world with better services and guaranteed products. Up to date, Gentolex Group has been serving customers from more than 10 countries, specially, representatives are established in Mexico and South Africa.

Our main services focus on supplying peptides APIs and Custom Peptides, FDF license out, Technical Support & Consultation, Product Line and Lab Setup, Sourcing & Supply Chain Solutions.

With an overall factory construction area of 250,000 square meters under international standards, we deliver flexible, scalable, and cost-effective solutions for global pharmaceutical and chemical clients.

Core Competencies & Services

  • Peptides APIs & Custom Peptide Synthesis
  • Pharmaceutical Intermediates & Chemical Products
  • FDF Licensing & Regulatory Dossier Support
  • Lab Setup, Procurement & Supply Chain Solutions

Authorized Logistics & Global Qualification Network

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Regulatory Compliance, Safety & Global Handling Standards

Ensuring full regulatory alignment, transport security, and environmental stewardship across all chemical shipments.

GHS Classification & Transport Safety

Ethylamino Ethanol (CAS 110-73-6) is classified as a flammable liquid (Category 3) and corrosive substance (Class 8 / UN 2735 or UN 1993 dependent on blend concentration). Safe handling requires adherence to ISO tank and drum packaging standards:

  • Standard Packaging: 200L High-Density Polyethylene (HDPE) drums, steel drums with phenolic internal linings, or 1000L ISO totes.
  • Storage Conditions: Store in dry, cool, well-ventilated areas away from strong oxidizing agents, acid anhydrides, and direct ignition sources.
  • Nitrogen Blanketing: Sealed under dry nitrogen gas protection to prevent atmospheric carbon dioxide absorption and color oxidation over extended storage cycles.

E-E-A-T Quality Documentation Package

To support seamless customs clearance and customer QA audits, every industrial shipment comes accompanied by a complete verification package:

  • Certificate of Analysis (CoA): Batch-specific GC purity, moisture content, density, and refractive index measurements.
  • Safety Data Sheet (SDS): 16-section multi-lingual GHS compliant SDS.
  • REACH & TSCA Declarations: Registration status compliance for EU and US markets.
  • BSE/TSE & Non-Animal Origin Certification: Suitable for sensitive biopharmaceutical precursor applications.

Frequently Asked Questions (FAQ) - Procurement & Technical Solutions

Addressing key questions regarding 2-(Ethylamino)ethanol manufacturing, quality control, purchasing terms, and technical specifications.

What is the standard purity level of your factory-supplied Ethylamino Ethanol?
Our standard commercial batch purity for Ethylamino Ethanol (CAS 110-73-6) is ≥ 99.5% determined via Gas Chromatography (GC-FID). For ultra-sensitive pharmaceutical applications or electronic chemical stripping, custom refinement up to 99.8% is available upon technical request.
How does Ethylamino Ethanol compare to Monoethanolamine (MEA) or Diethanolamine (DEA) in gas scrubbing?
Ethylamino Ethanol (N-Ethylethanolamine) features a steric ethyl substitution on the nitrogen atom. This secondary amine structure provides greater selectivity for hydrogen sulfide (H₂S) over carbon dioxide (CO₂) in gas sweetening processes, reduced energy consumption during heat regeneration cycles, and lower oxidative degradation rates compared to standard MEA.
Can Gentolex support custom synthesis or white-label OEM manufacturing for specialized peptide APIs and chemical intermediates?
Yes. Gentolex operates 250,000 square meters of international standard chemical and peptide synthesis infrastructure. We specialize in custom peptide synthesis, API building block development, FDF licensing, and full procurement supply chain services tailored to client specifications.
What documentation and compliance certifications accompany your chemical exports?
All shipments include batch-specific Certificates of Analysis (CoA), SDS (Safety Data Sheets compliant with GHS standards), REACH registration declarations for European markets, and origin verification certificates. cGMP compliance documentation is supplied for pharmaceutical API lines.
What are the recommended storage protocols to prevent color degradation of N-Ethylethanolamine?
To prevent dis-coloration caused by oxidation and trace carbon dioxide absorption, store Ethylamino Ethanol in tightly sealed steel or HDPE drums under a dry nitrogen blanket. Keep containers in a cool (below 30°C), dry, and well-ventilated storage warehouse away from direct sunlight.
What is the standard lead time for international bulk orders?
Standard inventory items are prepared for shipment within 3 to 7 business days. Custom chemical synthesis batches or bulk vessel/ISO tank deliveries generally require 2 to 4 weeks depending on production scheduling and regulatory export clearances.

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