Wholesale Sodium(+)-10-Camphorsulfonate Manufacturer & Supplier

Global Industrial Whitepaper: High-Purity Chiral Resolution Reagents, Advanced API Intermediates, & Next-Gen Chemical Supply Chain Architecture

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Executive Whitepaper: Sodium(+)-10-Camphorsulfonate Structural Overview & Market Dynamics

Comprehensive Analysis of Enantiomeric Separation, Chemical Kinetics, and Global B2B Supply Networks

"Sodium (+)-10-Camphorsulfonate (CAS 21791-94-6 / 3144-16-9) serves as an irreplaceable chiral resolving agent and chiral pool intermediate in modern pharmaceutical synthesis, asymmetric catalysis, and high-performance electrolyte formulations."

Chiral Resolution Mastery

Facilitates high-yield diastereomeric salt formation for basic racemic mixtures, enabling industrial-scale optical purity (>99.5% ee) in complex API manufacturing pipelines.

Industry 4.0 Precision

Produced under continuous-flow crystallization and automated process analytical technology (PAT), eliminating batch-to-batch specific rotation variance.

Global Compliance & Audit Ready

Fully backed by complete regulatory dossiers (CoA, MSDS, REACH registration, ISO9001/14001, and DMF documentation support for global pharma auditors).

≥ 99.0%
Assay Purity (HPLC)
+19.5°
Min Specific Rotation
250,000 m²
Standard Industrial Campus
10+
Global Representative Hubs

Technical Specifications & Chemical Identity Data

Empirical Chemical Metrics Validated by NMR, HPLC, and Chiral Chromatography Standards

Analytical Parameter Specification Standard Testing Methodology Quality Control Impact
Chemical Name Sodium (+)-10-camphorsulfonate / D-Camphorsulfonic Acid Sodium Salt IUPAC Nomenclature Primary Structural Identifier
CAS Registry Number 21791-94-6 / 3144-16-9 Chemical Abstracts Service Global Regulatory & Customs Index
Molecular Formula / Weight C10H15NaO4S / 254.28 g/mol Mass Spectrometry (MS) Stoichiometric Calculation Accuracy
Appearance White to Off-White Crystalline Powder Visual Inspection Color Consistency & Purity Indicator
Chemical Assay (HPLC) ≥ 99.0% (Dry Basis) High-Performance Liquid Chromatography Minimizes Unwanted Side-Reactions
Specific Optical Rotation [α]D20 +19.5° to +21.5° (c=5 in H2O) Polarimetry Guarantees Enantiomeric Excess (%ee)
Loss on Drying (LOD) ≤ 0.5% Karl Fischer / Gravimetric Prevents Hydrolytic Degradation
Heavy Metals (as Pb) ≤ 10 ppm ICP-MS Validation Pharma cGMP Impurity Limit Compliance

Industrial Applications & Global Use Scenarios

From Active Pharmaceutical Ingredient (API) Resolution to Functional Material Science

1. Pharmaceutical Chiral Resolution & API Intermediate

In the commercial synthesis of single-enantiomer therapeutics, Sodium (+)-10-Camphorsulfonate serves as a gold-standard chiral resolving agent. By forming diastereomeric salts with basic chiral compounds, chemical engineers achieve rapid fractional crystallization.

  • High resolution efficiency for racemic amines and amino derivatives.
  • Minimal racemization during salt formation and recovery cycles.
  • Fully compatible with large-scale cGMP crystallization reactors.

2. Advanced Battery & Electrolyte Additives

With the rapid expansion of energy storage technology, camphorsulfonate derivative salts are increasingly utilized as functional organic additives in non-aqueous electrolytes for lithium-ion and solid-state batteries.

  • Enhances Solid Electrolyte Interphase (SEI) film thermal stability.
  • Suppresses metal dendrite growth across high-voltage cathode interfaces.
  • Improves ionic conductivity under sub-zero operating environments.

3. Organic Synthesis & Asymmetric Catalysis

Acts as a chiral auxiliary and precursor in asymmetric phase-transfer catalysis. Its rigid bicyclic terpene framework provides effective steric hindrance, directing enantioselective addition, alkylation, and condensation reactions.

  • Key chiral template for high-value fine chemical building blocks.
  • Facilitates high diastereomeric ratios (dr) in total synthesis pathways.

4. Conductive Polymers & Optoelectronic Materials

Utilized as a functional dopant for polyaniline (PANI) and polypyrrole conductive matrices, tailoring polymer chain conformation and solubility in polar organic solvents for flexible electronics.

  • Imparts high electrical conductivity and anti-corrosive characteristics.
  • Enhances optical clarity and thermal stability in thin-film coatings.

China Factory 4.0: Supply Chain Resilience & Cost-Efficiency

Next-Generation Manufacturing Infrastructure Engineered for Uninterrupted Global Logistics

Automated Green Sulfonation

Our 250,000 m² state-of-the-art facility integrates micro-channel green continuous sulfonation technology, reducing solvent consumption while maximizing chemical yields by over 14% compared to traditional batch synthesis.

End-to-End Quality Traceability

From natural camphor raw material intake to final crystallizing, every batch undergoes automated inline NIR spectroscopy and HPLC testing, ensuring full compliance with ISO and global pharma standards.

Global Logistics & Local Presence

With direct regional representatives established in North America, Latin America (Mexico), and Africa (South Africa), Gentolex delivers seamless customs clearance, flexible MOQs, and resilient buffer stock solutions.

About Gentolex Enterprise & Global Capabilities

Connecting the World with Superior Chemical Services, cGMP APIs, and Custom Peptide Solutions

Gentolex’s goal is to create opportunities connecting the world with better services and guaranteed products. Up to date, Gentolex Group has been serving customers from more than 10 countries, specially, representatives are established in Mexico and South Africa. Our main services focus on supplying peptides APIs and Custom Peptides, FDF license out, Technical Support & Consultation, Product Line and Lab Setup, Sourcing & Supply Chain Solutions.

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Chemicals Products

An overall factory construction area of 250,000 square meters under international standard to offer flexible, scalable and cost-effective solutions.

Pharmaceutical Ingredients

Gentolex offers an extensive range of APIs and intermediates for development study and commercial application with cGMP standard from long-term collaborations. Documents and Certificates are supported to customers worldwide.

Development & Research

Advanced analytical testing, process optimization, custom synthesis, and scale-up engineering for fine chemical synthesis.

Procurement Service

For those clients who prefer to avoid the complexity of dealing with multiple points of contact, we provide extra customized procurement services with the most superior and comprehensive supply chain sources.

Manufacturing Facility Insights

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Quality Standards & Strategic Network

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Frequently Asked Questions (FAQ)

In-Depth Answers for Procurement Officers, QA Managers, and Chemical Process Engineers

Q1: What is the primary analytical difference between Sodium (+)-10-Camphorsulfonate and D-Camphorsulfonic Acid?

Sodium (+)-10-Camphorsulfonate (CAS 21791-94-6) is the sodium salt derivative of D-Camphorsulfonic Acid (CSA). While free CSA is highly hygroscopic and acidic, the sodium salt offers superior solid-state stability, non-corrosive handling characteristics, and predictable solubility profiles in aqueous and mixed polar organic solvent systems.

Q2: How does Gentolex guarantee high optical purity ([α]D20 ≥ +19.5°) across large manufacturing lots?

Optical purity is maintained by utilizing strictly enantiopure d-camphor raw feedstocks coupled with continuous optical rotation polarimetry during our multi-stage crystallization process. Every production lot is certified via Chiral HPLC to ensure zero racemization during manufacturing.

Q3: What standard packaging configurations are available for bulk commercial orders?

Our standard packaging includes 25 kg fiber drums lined with double anti-static PE bags. Custom packaging—ranging from 1 kg aluminum foil bags for laboratory testing to 500 kg super-sacks for high-volume industrial syntheses—is readily provided upon request.

Q4: What regulatory compliance documents accompany each shipment?

Every shipment includes a batch-specific Certificate of Analysis (CoA), Safety Data Sheet (SDS/MSDS) compliant with GHS regulations, Method of Analysis (MoA), stability testing summaries under ICH guidelines, and BSE/TSE-free certification.

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