High-purity building blocks, specialized peptides, and commercial-scale Active Pharmaceutical Ingredients (APIs) supporting global research and industrial synthesis.
2-Benzothiazolamine (CAS Registry Number: 136-95-8), also commonly identified as 2-aminobenzothiazole, represents a foundational bicyclic heterocycle containing fused benzene and thiazole rings. Featuring both an electrophilic thiazole carbon and a nucleophilic exocyclic amino group, 2-Benzothiazolamine serves as a versatile building block across advanced pharmaceutical synthesis, agrochemical formulation, vulcanization acceleration in elastomer processing, and organic photovoltaic dye development.
As premier OEM 2-Benzothiazolamine suppliers and exporters, Gentolex Group combines state-of-the-art synthetic chemistry with scalable multi-ton production capabilities. Our industrial infrastructure guarantees tight control over impurity profiles—specifically minimizing unreacted aniline, toxic heavy metals, and residual free sulfur—to meet the rigorous criteria established by global regulatory authorities including FDA, EMA, and PMDA.
| Parameter / Parameter Specification | High Purity API Grade | Industrial Technical Grade | Analytical Test Method |
|---|---|---|---|
| Chemical Name | 2-Benzothiazolamine / 2-Aminobenzothiazole | IUPAC Nomenclature | |
| CAS Registry Number | 136-95-8 | CAS Index | |
| Molecular Formula / Weight | C7H6N2S / 150.20 g/mol | High-Res Mass Spectrometry (HRMS) | |
| Assay Purity (HPLC) | ≥ 99.5% (Single impurity < 0.10%) | ≥ 98.5% | HPLC-UV / Reverse Phase Column |
| Appearance | Off-white to pale yellow crystalline powder | Light beige crystalline powder | Visual / Colorimetry |
| Melting Point Range | 129.0 °C – 131.0 °C | 127.0 °C – 130.0 °C | Capillary Melting Point Apparatus |
| Loss on Drying (Moisture) | ≤ 0.20% | ≤ 0.50% | Karl Fischer Titration / Infrared Balance |
| Residue on Ignition (Ash) | ≤ 0.10% | ≤ 0.30% | Gravimetric Analysis (800 °C) |
| Heavy Metals (as Pb) | ≤ 10 ppm | ≤ 20 ppm | ICP-MS Validation |
Gentolex operates modern synthetic chemical lines engineered for high yield, environmental sustainability, and high batch-to-batch reproducibility. The commercial synthesis of 2-Benzothiazolamine relies on optimized chemical pathways:
The reaction of aniline with ammonium thiocyanate yields phenylthiourea, which undergoes intramolecular oxidative cyclization in the presence of green halogenating agents or catalytic bromide/hydrogen peroxide systems.
Condensation of 2-aminothiophenol with cyanogen bromide or cyanamide under controlled pH and temperature conditions provides direct entry to ultra-pure 2-Benzothiazolamine.
Understanding that different industrial applications demand customized physical and chemical properties, Gentolex offers bespoke OEM solutions for 2-Benzothiazolamine buyers:
Micronized powders (D90 < 10 µm) for optimal dispersion in polymer matrices and elastomer vulcanization formulas, alongside granular non-dusting formats for safe handling.
UN-approved packaging options ranging from 25 kg fiber drums with double PE liners to 500 kg flexible intermediate bulk containers (FIBC) with antistatic coatings.
Synthesis of specialty salts (e.g., Hydrochloride, Hydrobromide) and functional derivatives under strict non-disclosure agreements (NDAs).
Analyzing the multi-sector demand driving international procurement of 2-Benzothiazolamine.
Serves as a pivotal structural core in neuroprotective drugs (such as Riluzole analogs), core pharmacophores for central nervous system (CNS) agents, novel anticonvulsants, and target-specific anti-tumor compounds.
Essential precursor for secondary vulcanization accelerators like 2-Mercaptobenzothiazole (MBT), Benzothiazole Sulfenamides (CBS, TBBS), enhancing rubber elasticity and heat endurance for global automotive tire manufacturers.
Key intermediate in the synthesis of next-generation fungicides, herbicides, and plant growth regulators designed to combat resistant fungal strains while meeting strict environmental safety levels.
Utilized in chromophore design for high-performance cyanine dyes, fluorescent markers, and light-harvesting organic sensitizers in dye-sensitized solar cells (DSSCs).
Connecting international buyers with certified chemical manufacturing and supply chain solutions.
Gentolex’s corporate mission centers on creating seamless, high-reliability commercial linkages across the global chemical landscape. With an overall factory construction footprint spanning 250,000 square meters built to international cGMP standards, Gentolex offers scalable, flexible, and cost-efficient chemical synthesis.
Today, Gentolex Group serves client networks in over 10 countries, featuring established regional hubs in Mexico and South Africa. Our expanded chemical capabilities include:
Complete synthesis capability from research-grade sequences to commercial API scale, utilizing advanced solid-phase and liquid-phase peptide synthesis (SPPS/LPPS) technologies.
Finished Dosage Form (FDF) licensing out, backed by comprehensive DMF documentation, CTD dossiers, and full regulatory consulting for global registration.
For clients seeking to reduce procurement complexity, we deliver streamlined supply chain management, laboratory setup services, and specialized sourcing for complex intermediates.
Gentolex adheres strictly to international quality management protocols, ensuring that every batch of 2-Benzothiazolamine shipped globally meets verifiable standard operating procedures.
Every commercial batch undergoes rigorous Quality Control (QC) screening prior to release:
The international market for 2-Benzothiazolamine is undergoing dynamic expansion, driven by rapid advancements in target therapeutics and durable high-performance polymers. Strategic insights reshaping global supply dynamics include:
With increasing research into heterocycle-derived neuroprotective and oncology therapeutics, demand for ultra-high purity (≥99.5%) 2-Benzothiazolamine as a key starting material (KSM) is expanding across North American and European pharma hubs.
As global automotive manufacturing shifts toward eco-friendly tire formulations, vulcanization chemistry demands accelerators free from nitrosamine precursors. 2-Benzothiazolamine-derived accelerators fulfill these enhanced regulatory standards.
To mitigate global supply chain disruptions, Gentolex’s localized operational nodes in Mexico and South Africa provide regional buffer stocks, reducing lead times for enterprise clients across the Americas and Africa.
Technical and commercial clarity for procurement managers, chemical engineers, and R&D leaders.
Standard catalog quantities are available for immediate dispatch from our regional warehouses. For multi-ton custom OEM production runs, standard lead times range from 2 to 4 weeks, inclusive of complete Certificate of Analysis (COA) testing and export compliance documentation.
Yes. We provide specialized mechanical processing, including air-jet micronization for ultra-fine particle sizes (D90 < 10 µm) and granulation technologies to produce free-flowing, dust-free granules tailored for automated industrial processing.
Every shipment is accompanied by a batch-specific Certificate of Analysis (COA), including HPLC purity spectrums, Loss on Drying (LOD) measurements, melting range verification, Heavy Metal analysis (ICP-MS), and residual solvent reports (GC-MS). Safety Data Sheets (SDS) in GHS format are available in multiple languages.
Gentolex maintains full REACH registration coverage for European markets via our Only Representative (OR) structure. We provide full compliance declarations and support EU importers with tonnage band allocations to ensure uninterrupted clearance.
2-Benzothiazolamine should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from strong oxidizing agents, acids, and direct sunlight. Under recommended ambient conditions (15–25°C), the compound exhibits a shelf life of 24 months.
Explore our extended catalog of high-purity peptides, active pharmaceutical ingredients, and industrial intermediates.
An overall factory construction area of 250,000 square meters under international standard to offer flexible, scalable and cost-effective solutions.
Gentolex offers an extensive range of APIs and intermediates for development study and commercial application with cGMP standard from long-term collaborations. Documents and Certificates are supported to customers worldwide.
Full support from laboratory synthesis to pilot plants and industrial-scale production runs backed by advanced reaction analytics.
For those clients who prefer to avoid the complexity of dealing with multiple points of contact, we provide extra customized procurement services with the most superior and comprehensive supply chain sources.
Latest scientific disclosures, product launches, and chemical manufacturing updates from Gentolex Group.
Selank Acetate API is a synthetic heptapeptide active pharmaceutical ingredient composed of the amino acid sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. Learn about our synthesis innovations...
Read Technical Article
As a professional Thymosin Beta-4 API manufacturer and supplier, we provide high-quality Tβ4 peptide API solutions for biotechnology and pharmaceutical R&D worldwide...
Read Technical Article
BPC-157 API is a synthetic pentadecapeptide that has gained increasing attention in peptide research due to its potential biological activities related to tissue repair...
Read Technical Article
With continuous developments in neuroscience and peptide technology, neuroactive peptides have become an important focus area. Discover Semax API parameters...
Read Technical Article
SS-31 API (Elamipretide, MTP-131) is a synthetic mitochondria-targeting tetrapeptide designed to bind cardiolipin in the inner mitochondrial membrane to stabilize bioenergetics...
Read Technical Article
